"The first week I started the regime the change was amazing. My energy returned, my skin glowed, the aches and pains and heat (inflammation) in my joints went away (almost all), the gastric reflux stopped. People commented on the change in me. I was amazed at how different and positive I felt. So thank you so much." Susie, Plymouth

"I can't speak highly enough of that man, he changed my life". Doreen, Worcester 

Detoxification

Everyday exposure to a host of chemicals from our environment, from our diet, from our lifestyle, from medication or even chemicals we produce from a multitude of natural biological processes within the body, need to be expelled before they can cause us problems. This is the process of detoxification and it is usually in two parts or phases: Phase 1 detoxification and phase 2 detoxification.

Phase 1 detoxification – Also called hydroxylation, it is the process of converting a chemical which is not water soluble and therefore not easily carried in the blood – water based, and making it available for binding with a water soluble molecule to help with its eventual excretion.

The enzymes which carry out phase 1 detoxification are controlled by a set of genes called cytochrome p450 and p448. This naturally means that some people who have a variation of these genes would be more susceptible than others to certain chemicals.
The process of detoxification in susceptible people results in the production of an intermediate chemical far more potent than the original which is being detoxified and poses a threat to the very life of the individual.

A prime example of this susceptibility is in the detoxification of the most widely used pain killer of recent times: paracetamol or acetaminophen. 10-15% of the general population have a variant of cytochrome p450 which could become life threatening from taking the normal dose of this drug - 2-4 tablets 2-3 times per day. In fact this reaction happens to be the most common non trauma emergency in hospitals.

Phase 2 detoxification – Also called conjugation and is the continuation process to phase 1 detoxification. The resultant chemical is combined with another water soluble molecule rendering it harmless which is then finally expelled from the body in the urine.

The process of conjugation is a straightforward chemical reaction using molecules such as sulphates (sulphation), a methyl group (methylation), a glucoronate (glucoronidation) and so on. All these essential chemicals for conjugation or phase 2 detoxification are obtained from a healthy balanced diet and especially from fresh fruits and vegetables.   
  
An Integral Health DNA Hair Test not only can identify the cause/causes of an imbalance in the body and the potential for signs and symptoms of disease; we are also able to provide the best nutrient and lifestyle recommendations specifically tailored for each unique individual, helping to ensure they are able to achieve optimum health – naturally.
It is a blueprint for healthy living. 

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